Mechanism

Prevents the liver synthesis of vitamin K dependent factors (2, 7, 9, 10)

Monitor

Coumadin (Warfarin) is monitored by PT, "WEPT"

Uses

Anticoagulation for: 

1. post myocardial infarction
2. mechanical heart valves
3. thrombosis prevention in atrial fibrillation
4. post PE/DVT